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Study details
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A Study of Orforglipron (LY3502970) in Adolescent Participants With Obesity, or Overweight With Related Comorbidities

Eli Lilly and Company
NCT IDNCT06672939ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

125

Study length

about 2.4 years

Ages

12–17

Locations

15 sites in CA, CT, GA +9

About this study

Researchers are testing a treatment called orforglipron versus a placebo in adolescents with obesity or overweight and related health problems. The trial will last about 18 months.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Orforglipron
  • 2.Take Placebo
PhasePhase 3
DrugOrforglipron
Primary goalPercent Change from Baseline in Body Mass Index (BMI)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low8%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Percent Change from Baseline in Body Mass Index (BMI)

Secondary: Change from Baseline in BMI, Change from Baseline in Body Weight, Change from Baseline in Body Weight Percentile, Change from Baseline in Diastolic Blood Pressure, Change from Baseline in Fasting Glucose, Change from Baseline in Systolic Blood Pressure, Change from Baseline in Waist Circumference, Change in Impact of Weight on Quality of Life (IWQOL)-Kids Total and Domain Scores

Body systems

Endocrinology