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Study details
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Evaluation Of Semaglutide in Adults With Cocaine Use Disorder With and Without HIV

University of Maryland, Baltimore
NCT IDNCT06691243ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

40

Study length

about 1.6 years

Ages

18–65

Locations

2 sites in DC, MD

About this study

This trial is testing whether semaglutide is safe and well-tolerated in adults with cocaine use disorder, both with and without HIV. Participants will receive either semaglutide or a placebo for 601 days.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Placebo
  • 2.Take Semaglutide
PhasePhase 2
DrugSemaglutide
Routeoral
Primary goalTolerability of semaglutide in patients with cocaine use disorder (CUD) with and without HIV

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low10%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

semaglutide (GLP-1 agonist; stimulates insulin release)

Drug routes

oral (Oral Tablet)

Endpoints

Primary: Tolerability of semaglutide in patients with cocaine use disorder (CUD) with and without HIV

Body systems

Immune, Infectious