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Study details
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A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder

AbbVie
NCT IDNCT06696755ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Ages

18–65

Locations

29 sites in AL, AR, AZ +10

About this study

This Phase 2 study is focused on people with bi polar ii disorder. The primary outcome being measured is Change from Baseline to Week 6 in the MADRS (Montgomery-Åsberg Depression Rating Scale) total score.

Based on ClinicalTrials.gov records.

PhasePhase 2
Primary goalChange from Baseline to Week 6 in the MADRS (Montgomery-Åsberg Depression Rating Scale) total score

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low9%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Change from Baseline to Week 6 in the MADRS (Montgomery-Åsberg Depression Rating Scale) total score, Number of Participants with Adverse Events (AEs)

Secondary: Change from Baseline to Week 6 in Clinician Global Impression of Severity - Bipolar Disorder (CGI-S-BP) score

Body systems

Psychiatry / Mental Health