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Study details
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Memantine and Exercise to Improve Cognitive Function

UNC Lineberger Comprehensive Cancer Center
NCT IDNCT06727773ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

90

Study length

about 3.5 years

Ages

18+

Sex

Female only

Locations

1 site in NC

About this study

Researchers are testing whether memantine and exercise can improve cognitive function in breast cancer patients undergoing chemotherapy. The trial will evaluate the feasibility, acceptability, and preliminary efficacy of a combination treatment with memantine and an exercise program on cognitive decline and related biomarkers.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Exercise Control
  • 2.Exercise Intervention
  • 3.Take Memantine
  • +1 more
PhasePhase 2
DrugMemantine

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low7%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

memantine

Body systems

Oncology