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Study details
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Anxiety During Abstinence in Alcohol Use Disorder

Columbia University
NCT IDNCT06793488ClinicalTrials.gov data as of Apr 2026
Phase

EARLY_PHASE1

Target enrollment

60

Study length

about 4 years

Ages

21–55

Locations

1 site in NY

About this study

This trial is testing how anxiety changes during abstinence in people with alcohol use disorder (AUD). Researchers will give some participants disulfiram to help them stay abstinent and scan their brains using fMRI. They are also comparing this to healthy volunteers who do not receive disulfiram.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Disulfiram 250 mg
  • 2.Undergo functional MRI
PhaseEARLY_Phase 1
DrugDisulfiram 250 mg
Routeoral

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low13%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

disulfiram

Drug routes

oral (Oral Tablet)

Procedures

imaging

Body systems

Psychiatry / Mental Health