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Study details
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A Prospective Trial of Dalbavancin-Based Prophylaxis in Children and Adolescents With High-Risk Leukemia

St. Jude Children's Research Hospital
NCT IDNCT06810583ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

29

Study length

about 5.4 years

Ages

≤25

Locations

1 site in TN

About this study

This trial is testing dalbavancin, a medication, as a preventative measure against bacterial infections in children and adolescents with leukemia who are receiving chemotherapy. The goal is to see how effective this treatment is at preventing bloodstream infections and other complications.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Dalbavancin
  • 2.Take Fluoroquinolone (either ciprofloxacin or levofloxacin at the discretion of the treating clinician)
PhasePhase 1
DrugDalbavancin
Routeinjection

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low11%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

dalbavancin, antibiotic (Fluoroquinolone antibiotic; inhibits bacterial DNA gyrase)

Drug routes

injection, intravenous, oral (Oral Tablet)

Endpoints

Secondary: Dalbavancin peak plasma concentration (Cmax) - Median and range, Tolerability of dalbavancin

Body systems

Oncology