Skip to content
Study details
Enrolling now

Imaging Skeletal Muscle Mitochondrial OXPHOS Activity In Acute Lymphoblastic Leukemia Survivors

St. Jude Children's Research Hospital
NCT IDNCT06819475ClinicalTrials.gov data as of Apr 2026
Target enrollment

60

Study length

about 2.7 years

Ages

18+

Locations

1 site in TN

About this study

This trial is testing how skeletal muscle mitochondria function in people who have survived acute lymphoblastic leukemia (ALL). It involves imaging techniques and blood tests to compare muscle health between ALL survivors and a control group. The goal is to understand the relationship between cancer treatment, muscle weakness, and mitochondrial activity.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Magnetic Resonance Spectroscopy
  • 2.Peripheral blood sample
  • 3.Physical function assessment
  • +3 more
Primary goalTo explore feasibility of CrCEST MRI to measure OXPHOS capacity

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low10%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: To explore feasibility of CrCEST MRI to measure OXPHOS capacity, To explore feasibility of Fat Fraction MRI to measure OXPHOS capacity, To explore feasibility of MRI/MRS to measure OXPHOS capacity, To explore feasibility of Muscle Ultrasound to measure OXPHOS capacity

Procedures

imaging

Body systems

Oncology