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Study details
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Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult Patients With Moderate to Severe Hidradenitis Suppurativa

Novartis Pharmaceuticals
NCT IDNCT06840392ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

555

Study length

about 3.6 years

Ages

12–100

Locations

36 sites in AL, AZ, CA +15

About this study

This trial is testing a treatment called remibrutinib compared to placebo in adults with moderate to severe hidradenitis suppurativa. The goal is to see if this treatment is effective, safe, and well-tolerated.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Placebo 1
  • 2.Take Placebo 2
  • 3.Take Remibrutinib Dose A
  • +1 more
PhasePhase 3
DrugRemibrutinib Dose A
Routeoral

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low10%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS

Drug routes

oral (Oral Tablet)

Endpoints

Secondary: Incidence of treatment emergent adverse events and serious adverse events during the study, Percentage change from baseline in International Hidradenitis Suppurativa Severity Score System (IHS4) at Week 16, Proportion of participants with clinical response in HS related skin pain (NRS 30), at worst at Week 16