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Study details
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A Pivotal Study to Evaluate the Effectiveness of Isometric Handgrip Therapy in Elevated Blood Pressure and Hypertensive Subjects

Zona Health, Inc
NCT IDNCT06843577ClinicalTrials.gov data as of Apr 2026
Target enrollment

160

Study length

about 2.2 years

Ages

22+

Locations

5 sites in CA, FL, IL +2

About this study

Researchers are testing whether using a handgrip device or relaxing music can help lower blood pressure. The trial will involve adults with high blood pressure who are not already taking medication for their condition. Participants will use either the handgrip device or listen to relaxing music, and some will also monitor their blood pressure at home.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Relaxing Music App
  • 2.Use Zona Plus Device
Primary goalCompare the change from baseline in mean seated cuff systolic blood pressure (SBP) after 10 weeks of treatment between patients randomized to the Zona Plus device and the patients in the control group

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low12%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Compare the change from baseline in mean seated cuff systolic blood pressure (SBP) after 10 weeks of treatment between patients randomized to the Zona Plus device and the patients in the control group.

Secondary: To compare the change from baseline in seated cuff diastolic blood pressure (DBP) after 10 weeks of treatment between patients randomized to the Zona Plus device and the patients in the control group.

Body systems

Cardiology / Heart