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Study details
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NE3107 Trial in Adults with Long COVID Symptoms

BioVie Inc.
NCT IDNCT06847191ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

208

Study length

about 9 months

Ages

18–69

Locations

20 sites in CA, CO, CT +14

About this study

This trial is testing NE3107, a medication, to see if it helps treat neurological symptoms like brain fog and fatigue that can persist after a COVID-19 infection. Researchers will compare NE3107 to a placebo (a look-alike substance) to determine if NE3107 works to improve neurocognitive and fatigue symptoms of long COVID. Participants will take NE3107 or a placebo twice daily for 84 days, visit the clinic multiple times for checkups and tests, and have follow up phone calls.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take NE3107
  • 2.Take Placebo
PhasePhase 2
Primary goalChange from Baseline in performance on the Cogstate Cognition battery

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low6%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Change from Baseline in performance on the Cogstate Cognition battery

Secondary: Change from Baseline in DePaul Symptom Questionnaire (DSQ) Post-Exertional Malaise (PEM, Change from Baseline in PROMIS Cognitive Function Short Form 8a (SF-8a), Change from Baseline in PROMIS Fatigue Short Form 13a (SF-13a), Change from Baseline in PROMIS Sleep Disturbance Short Form 8a (SF-8a), Change from Baseline in SF-12 Health Survey (Physical and Mental Component Scores)