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Study details
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A Study to Assess the Efficacy and Safety of Afimkibart (RO7790121) in Participants With Moderate to Severe Atopic Dermatitis

Hoffmann-La Roche
NCT IDNCT06863961ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

160

Study length

about 1.7 years

Ages

18+

Locations

25 sites in CA, FL, GA +12

About this study

Researchers are testing a treatment called Afimkibart (also known as RO7790121) for people with moderate to severe atopic dermatitis. The trial will last 604 days and involve approximately 160 participants.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Afimkibart
  • 2.Take Placebo
PhasePhase 2

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low6%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Secondary: Change from Baseline in Dermatology Quality of Life Index at Week 16, Week 32 and by Visit, Percent Change from Baseline in EASI by Visit, Percent Change from Baseline in Peak Pruritus Numerical Rating Scale (NRS) Score by Visit, Percentage of Participants with Adverse Events

Body systems

Dermatology