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Study details
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A Study to Assess the Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis Treated With Risankizumab Compared to Vedolizumab

AbbVie
NCT IDNCT06880744ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

530

Study length

about 3.3 years

Ages

18–80

Locations

74 sites in AL, AZ, CA +24

About this study

Researchers are testing whether risankizumab or vedolizumab are effective treatments for adults with moderate to severe ulcerative colitis who haven't received targeted therapies before. The trial will last about 69 weeks, and participants will receive either risankizumab (IV then subcutaneous) or vedolizumab (IV throughout).

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Risankizumab
  • 2.Take Vedolizumab
PhasePhase 3
DrugRisankizumab
Routeinjection

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low5%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

risankizumab, vedolizumab

Drug routes

injection, intravenous

Body systems

Gastroenterology