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Study details
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A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

Eli Lilly and Company
NCT IDNCT06897475ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

240

Study length

about 1.8 years

Ages

18–75

Locations

25 sites in AZ, CA, FL +11

About this study

Researchers are testing whether LY3457263, compared to placebo, can help lower hemoglobin A1c (HbA1c) levels in adults with type 2 diabetes who are already taking semaglutide or tirzepatide. The trial will last about 9 months.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take LY3457263
  • 2.Take Placebo
PhasePhase 2
Primary goalChange from Baseline in Hemoglobin A1c (HbA1c)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low9%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Change from Baseline in Hemoglobin A1c (HbA1c)

Secondary: Change from Baseline in Fasting Serum Glucose, Percent Change from Baseline in Body Weight

Body systems

Endocrinology