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Study details
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A Study of MET233 in Combination With MET097

Metsera, a wholly owned subsidiary of Pfizer
NCT IDNCT06924320ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1/2

Target enrollment

132

Study length

about 11 months

Ages

18–75

Locations

1 site in CA

About this study

Researchers are testing a treatment combination (MET233 and MET097) for people with obesity or overweight, possibly including those with diabetes. The trial will examine the safety and how well the medication works in the body.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take MET233
  • 2.Take MET233 and MET097
  • 3.Take Placebo
PhasePhase 1/Phase 2
Primary goalPart A: Occurrence of treatment-emergent adverse events (TEAEs)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low14%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Part A: Occurrence of treatment-emergent adverse events (TEAEs), Part B: Occurrence of treatment-emergent adverse events (TEAEs), Part C: Occurrence of treatment-emergent adverse events (TEAEs)

Secondary: Part A: Area under the concentration versus time curve (AUC), Part A: Maximum observed concentration (Cmax), Part A: Percent change from baseline in body weight, Part A: Time to maximum observed concentration (Tmax), Part B: Area under the concentration versus time curve (AUC), Part B: Maximum observed concentration (Cmax), Part B: Percent change from baseline in body weight, Part B: Time to maximum observed concentration (Tmax)

Body systems

Endocrinology