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Study details
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Long Covid (LC)-REVITALIZE - A Long Covid Repurposed Drug Study

Douglas D. Fraser
NCT IDNCT06928272ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

348

Study length

about 2.3 years

Ages

18–65

Locations

1 site in CA

About this study

This trial is testing repurposed drug treatments for Long Covid in adults. Participants will take either pirfenidone, upadacitinib, or a placebo for 842 days to see if the drugs improve symptoms like fatigue and breathing. It aims to assess the safety and effectiveness of these treatments.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Pirfenidone
  • 2.Take Placebo for pirfenidone
  • 3.Take Placebo for upadacitinib
  • +1 more
PhasePhase 3
Drugpirfenidone
Routeoral
Primary goalSymptom Burden Questionnaire (SBQ) Subscales

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low15%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

pirfenidone, upadacitinib

Drug routes

oral (Oral Tablet), oral (Oral Solution)

Endpoints

Primary: Symptom Burden Questionnaire (SBQ) Subscales

Secondary: Exercise capacity assessed by the 6-minute walk test (6MWT), General participant reported overall well-being using the Patient Reported Outcome Measurement Information System (PROMIS)-29 questionnaire, Safety and tolerability of the study drugs in participants with Long Covid, Worsening Long Covid Symptoms Measured by SBQ Subscales