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Study details
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Mirikizumab and Tirzepatide Trial

Eli Lilly and Company
NCT IDNCT06937086ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

350

Study length

about 2.8 years

Ages

18–70

Locations

37 sites in AL, CA, FL +20

About this study

Researchers are testing whether a combination of mirikizumab and tirzepatide, compared to mirikizumab alone, helps reduce or eliminate symptoms of ulcerative colitis (UC) in adults with UC and obesity. The trial will last up to 61 weeks, including 52 weeks of treatment.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Mirikizumab
  • 2.Take Placebo
  • 3.Take Tirzepatide
PhasePhase 3
DrugMirikizumab
Routeinjection

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low9%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

mirikizumab, tirzepatide

Drug routes

injection (Injection)

Endpoints

Secondary: Percentage of Participants Who Achieve Bowel Movement Urgency Improvement Captured with Urgency Numeric Rating Scale (NRS)

Body systems

Endocrinology, Gastroenterology