Skip to content
Study details
Enrolling now

BXCL501 After Stress to Increase Recovery Success

University of North Carolina, Chapel Hill
NCT IDNCT06943404ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

100

Study length

about 1.1 years

Ages

18–65

Locations

3 sites in FL, MO, VA

About this study

This trial is testing if BXCL501 helps reduce symptoms of Acute Stress Reaction (ASR) and Acute Stress Disorder (ASD) in adults who have experienced a motor vehicle collision. Participants will receive BXCL501 or a placebo after the accident, and their symptoms, cognitive function, and any side effects will be monitored over 396 days.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take BXCL501 (dexmedetomidine HCl)
  • 2.Take Placebo
PhasePhase 2
DrugBXCL501 (dexmedetomidine HCl)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low13%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

dexmedetomidine, Anesthetics (Adrenergic alpha1-Agonists)

Endpoints

Secondary: Change in Depressive Symptoms Score, Change in PTSD Symptoms, Change in Pain Symptom Score, Change in Somatic Symptom Score

Body systems

Psychiatry / Mental Health