Multiphase Optimization Strategy (MOST) for Treating Pediatric Post-traumatic Stress Disorder (PTSD)
200
about 2.6 years
8–17
1 site in NY
About this study
Researchers are testing different treatment components to improve pediatric post-traumatic stress disorder (PTSD). The trial will also provide evidence on how these components work. Researchers will compare the components to a psychological placebo and examine their effects alone and in combination with other components.
Based on ClinicalTrials.gov records.
What participants do
- 1.Participate in Bi-lateral Stimulation
- 2.Participate in Cognitive Processing
- 3.Participate in Emotion Regulation
- +2 more
Participation effort
Estimated from trial records. Details can vary by site.
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
Primary: Mean Change in PTSD Symptoms - Child PTSD Symptom Scale for DSM-5 (CPSS), Mean Change in PTSD Symptoms - Child and Adolescent Trauma Screen (CATS-2), Mean Change in PTSD Symptoms - Clinician Administered PTSD Scale for DSM-5 - Child/Adolescent Version (CAPS-CA)
Secondary: Brain Aging - Magnetic Resonance Imaging (MRI), Change in Network Connectivity - Magnetic Resonance Imaging (MRI), Change in Neural Structure - Magnetic Resonance Imaging (MRI), Change in PTSD Symptom Trajectories - Child PTSD Symptom Scale for DSM-5 (CPSS), Change in PTSD Symptom Trajectories - Child and Adolescent Trauma Screen (CATS-2), Change in PTSD, Mood, Anxiety, and Disruptive Behavior Disorder Symptom Trajectories - Ecological Momentary Assessment (EMA), Changes in Trajectories of C-Reactive Protein (CRP), Changes in Trajectories of Interleukin-6 (IL-6)
therapy
Psychiatry / Mental Health, Oncology