Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study
Phase 4
1,335
about 4.4 years
18–70
23 sites in AZ, CA, CO +15
About this study
This trial is testing the effectiveness of three migraine preventive medications: atogepant, propranolol, and topiramate. Participants will be randomly assigned to take one of these medications for 1606 days while tracking their headaches with a daily diary.
Based on ClinicalTrials.gov records.
What participants do
- 1.Take Atogepant 60 mg
- 2.Take Propranolol 160 mg
- 3.Take Topiramate 100 mg
Participation effort
Estimated from trial records. Details can vary by site.
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
atogepant, propranolol (Non-selective beta blocker; slows heart rate), topiramate
oral (Oral Tablet)
Secondary: Medication-Related Adverse Events, Migraine Specific Quality-of-Life - Role Function-Restrictive
Neurology