Study details
Enrolling now
Sinonasal Therapies and Histologic Correlations of Patients With Cystic Fibrosis in the Era of Highly Effective Modulator Therapy
Indiana University
NCT IDNCT06996951ClinicalTrials.gov data as of Apr 2026
Phase
Phase 3
Target enrollment
64
Study length
about 1.1 years
Ages
18+
Locations
1 site in IN
About this study
Researchers are testing whether people with Cystic Fibrosis on highly effective modulator therapy can stop using certain sinus treatments like nasal saline irrigation, steroid sprays, and antibiotic sprays. The trial will also examine changes in fluid inside the nose when these treatments are stopped.
Based on ClinicalTrials.gov records.
What participants do
- 1.Take CONTINUE NASAL SALINE IRRIGATION WITH OR WITHOUT STEROID
- 2.Use STOP NASAL SALINE IRRIGATION WITH OR WITHOUT STEROID
PhasePhase 3
DrugCONTINUE NASAL SALINE IRRIGATION
Primary goalChange in Body Mass Index (BMI)
Participation effort
Estimated from trial records. Details can vary by site.
Time + visits
Low6%
Logistics
Moderate50%
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
Drug classes
corticosteroid
Drug routes
intranasal
Endpoints
Primary: Change in Body Mass Index (BMI), Change in Patient Health Questionnaire-9 (PHQ-9) Score
Body systems
Respiratory