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Study details
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A Phase III Trial of AZD0780 on Major Adverse CV Events

AstraZeneca
NCT IDNCT07000357ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

15,100

Study length

about 4.4 years

Ages

18+

Locations

293 sites in AL, AZ, CA +38

About this study

Researchers are testing whether AZD0780, a medication, reduces the risk of major adverse cardiovascular events (MACE) in people who have already had heart problems or are at high risk for developing them. The trial will last 1605 days and involve approximately 15100 participants.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take AZD0780
  • 2.Take Placebo
PhasePhase 3
Primary goalTime to first event of any component of MACE-PLUS

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low6%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Time to first event of any component of MACE-PLUS

Secondary: Time to first event of any component of 3P MACE, Time to first event of any component of MACE PLUS

Body systems

Cardiology / Heart