Study details
Enrolling now
Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures
Major Extremity Trauma Research Consortium
NCT IDNCT07006675ClinicalTrials.gov data as of Apr 2026
Phase
Phase 3
Target enrollment
1,000
Study length
about 5.8 years
Ages
18–80
Locations
13 sites in IN, MA, MD +9
About this study
This trial is testing whether adding NSAIDs to standard pain management improves outcomes in people with tibial shaft fractures. It compares two groups: one group receives standard pain treatment without NSAIDs, while the other group also takes NSAIDs for up to six weeks.
Based on ClinicalTrials.gov records.
What participants do
- 1.Take 600 mg Ibuprofen
PhasePhase 3
Drug600 mg Ibuprofen
Routeoral
Participation effort
Estimated from trial records. Details can vary by site.
Time + visits
Low10%
Logistics
Moderate50%
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
Drug classes
ibuprofen
Drug routes
oral
Endpoints
Secondary: Persistent Pain & Pain Inference, Radiographic bone union