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Study details
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A Study to See How Well Lebrikizumab Works in Adults and Adolescents With Moderate Atopic Dermatitis (Eczema) and High Itch Burden

Eli Lilly and Company
NCT IDNCT07006792ClinicalTrials.gov data as of Apr 2026
Phase

Phase 4

Target enrollment

200

Study length

about 1.3 years

Ages

12+

Locations

35 sites in AL, AZ, CA +13

About this study

Researchers are testing how well lebrikizumab works for adults and adolescents with moderate atopic dermatitis, a condition causing itchy skin. The trial will last up to 38 weeks, including 6 months of treatment.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Lebrikizumab
PhasePhase 4
DrugLebrikizumab
Primary goalPercentage of Participants Achieving Eczema Area and Severity Index-75 (EASI-75) (≥75% Reduction from Baseline in EASI), or a ≥4-point Reduction in Pruritus Numerical Rating Scale (NRS) from Baseline

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low10%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

lebrikizumab

Endpoints

Primary: Percentage of Participants Achieving Eczema Area and Severity Index-75 (EASI-75) (≥75% Reduction from Baseline in EASI), or a ≥4-point Reduction in Pruritus Numerical Rating Scale (NRS) from Baseline

Secondary: Change from Baseline in Body Surface Area (BSA) Involvement, Change from Baseline in Children's Dermatology Quality of Life (CDLQI), Change from Baseline in Dermatology Quality of Life (DLQI), Percentage Change from Baseline in Sleep-loss Scale, Percentage of Change from Baseline in Pruritus NRS Score, Percentage of Participants Achieving a ≥4-point Reduction from Baseline in Pruritus NRS, Percentage of Participants with a Skin Pain NRS of ≥4 Points at Baseline Who Achieve a ≥4-point Reduction

Body systems

Dermatology