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Study details
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Self-regulation of Real-time fMRI Brain Activity in Chronic Pain

Brigham and Women's Hospital
NCT IDNCT07023523ClinicalTrials.gov data as of Apr 2026
Target enrollment

36

Study length

about 9 months

Ages

18–65

Locations

1 site in MA

About this study

This trial is testing if self-regulating brain activity can help people with fibromyalgia. Participants will use real-time fMRI neurofeedback to observe and control their own brain activity while using mental strategies to reduce pain. It involves MRI scans, neurofeedback tasks, and weekly sessions with a pain psychologist.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Participate in Cognitive Behavioral Therapy
  • 2.Participate in Disease Education
Primary goalChanges in brain activity in pain-associated regions such as vPCC/RSC

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low7%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Changes in brain activity in pain-associated regions such as vPCC/RSC

Secondary: Brief Pain Inventory (BPI), Pain Catastrophizing Scale (PCS)

Procedures

therapy

Body systems

Musculoskeletal