Spironolactone Trial to Improve Pregnancy-Associated Hypertension
Phase 2
204
about 3.4 years
18+
Female only
3 sites in MA, PA
About this study
Researchers are testing whether spironolactone, a medication that blocks the mineralocorticoid receptor, can improve blood pressure and heart health in women who have had gestational hypertension or preeclampsia. The trial will last for 1233 days (about three years) after delivery.
Based on ClinicalTrials.gov records.
What participants do
- 1.Take Placebo tablet to match spironolactone
- 2.Take spironolactone 25 mg orally once daily
Participation effort
Estimated from trial records. Details can vary by site.
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
diuretic (Potassium-sparing diuretic; aldosterone antagonist)
oral (Oral Tablet), oral
Primary: Mean 24-hour ambulatory diastolic blood pressure
Secondary: Mean 24-hour ambulatory systolic blood pressure, Mean diurnal ambulatory diastolic blood pressure, Mean diurnal ambulatory systolic blood pressure, Mean nocturnal ambulatory diastolic blood pressure, Mean nocturnal ambulatory systolic blood pressure, Measured diastolic blood pressure, Measured systolic blood pressure, N-terminal pro-B-type natriuretic peptide
Reproductive Health, Cardiology / Heart