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Study details
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Prehabilitation With Aerobic and Resistance Exercise for Improving Physical Fitness and Quality of Life Outcomes in Older Patients Undergoing CAR-T Therapy for Relapsed or Refractory Multiple Myeloma

Mayo Clinic
NCT IDNCT07045727ClinicalTrials.gov data as of Apr 2026
Target enrollment

20

Study length

about 1.1 years

Ages

60+

Locations

1 site in MN

About this study

This trial is testing whether prehabilitation with aerobic and resistance exercise improves physical fitness and quality of life outcomes in older patients planning to undergo chimeric antigen receptor (CAR)-T therapy for multiple myeloma that has come back after a period of improvement (relapsed) or that does not respond to treatment (refractory). Prehabilitation programs use targeted interventions to improve functional status prior to medical treatments. In it, patients participate in personalized aerobic and resistance prehabilitation activities in the weeks leading up to their CAR-T infusion. This program may improve physical fitness and quality of life, both prior to and after CAR-T infusion, in older patients with relapsed or refractory multiple myeloma.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Aerobic Exercise
  • 2.Electronic Health Record Review
  • 3.Internet-Based Intervention
  • +3 more
Primary goalChange in muscle strength

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low7%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Change in muscle strength, Change in quality of life - EORTC QLQ-C30, Enrollment rate, Incidence of adverse events, Patient satisfaction, Retention rate

Procedures

diagnostic

Body systems

Oncology