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Study details
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Intranasal and Intravenous Oxytocin for Analgesia to Noxious Heat Pain

Wake Forest University Health Sciences
NCT IDNCT07053774ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

24

Study length

about 11 months

Ages

18–75

Locations

1 site in NC

About this study

Researchers are testing whether oxytocin helps reduce pain from heat. Participants will receive oxytocin or a placebo through the nose or vein, and rate their pain levels after each treatment. The trial will last about 329 days.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Receive Intravenous oxytocin
  • 2.Receive Intravenous placebo
  • 3.Take Intranasal oxytocin
  • +1 more
PhasePhase 2
DrugIntravenous oxytocin
Routeintranasal
Primary goalPain Scale Score - During Skin Heating

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low11%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

oxytocin (Hormone; causes uterine contractions)

Drug routes

intranasal, infusion

Endpoints

Primary: Pain Scale Score - During Skin Heating, Pain Scale Score - End of 5-minute Skin Heating

Secondary: Pain Scale Score - During Skin Heating