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Study details
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A Study to Evaluate KarXT Injection

Bristol-Myers Squibb
NCT IDNCT07061288ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

48

Study length

about 2.1 years

Ages

18–55

Locations

8 sites in CA, FL, GA +3

About this study

Researchers are testing different doses of KarXT, a medication, to see how safe it is and what levels are reached in the body. The trial will last for about 772 days.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take KarXT
PhasePhase 1
DrugKarXT
Primary goalNumber of participants with adverse events (AEs)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low7%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Number of participants with adverse events (AEs), Number of participants with adverse events of special interest (AESIs), Number of participants with serious adverse events (SAEs)

Secondary: Apparent terminal phase half-life (T-HALF), Apparent total body clearance (CLT/F), Area under the plasma concentration-time curve from time zero to 672 hours (AUC(0-672)), Area under the plasma concentration-time curve from time zero to infinity (AUC(INF)), Area under the plasma concentration-time curve from time zero to time of last quantifiable concentration (AUC(0-T)), Maximum concentration (Cmax), Number of participants with AEs, Number of participants with SAEs

Body systems

Psychiatry / Mental Health