Study details
Enrolling now
Oral Steroid Taper After Total Knee Arthroplasty
Columbia University
NCT IDNCT07070882ClinicalTrials.gov data as of Apr 2026
Phase
Phase 1
Target enrollment
130
Study length
about 2 years
Ages
18+
Locations
1 site in NY
About this study
This trial is testing if an oral methylprednisolone taper helps reduce pain, opioid use, and nausea after knee replacement surgery. The goal is to see if adding this treatment to standard care improves outcomes for people undergoing total knee arthroplasty (TKA) for osteoarthritis.
Based on ClinicalTrials.gov records.
What participants do
- 1.Take Methylprednisolone
PhasePhase 1
DrugMethylprednisolone
Routeinjection
Participation effort
Estimated from trial records. Details can vary by site.
Time + visits
Low11%
Logistics
Moderate50%
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
Drug classes
methylprednisolone
Drug routes
injection (Injection)
Body systems
Musculoskeletal