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Study details
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A Study of JNJ-78278343 and JNJ-95298177 for Prostate Cancer

Janssen Research & Development, LLC
NCT IDNCT07082920ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

140

Study length

about 2.2 years

Ages

18+

Sex

Male only

Locations

4 sites in FL, NY, OH +1

About this study

This trial is testing a treatment combination (JNJ-78278343 and JNJ-95298177) to see if it's safe and effective in treating prostate cancer. The goal is to find the best dose of this combination for people with advanced, hormone-resistant prostate cancer.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take JNJ-78278343
  • 2.Take JNJ-95298177
PhasePhase 1
Primary goalNumber of Participants With Adverse Events (AEs) by Severity

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low8%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Number of Participants With Adverse Events (AEs) by Severity, Part 1: Number of Participants With Dose-Limiting Toxicity (DLT)

Secondary: Duration of Response (DOR), Objective Response Rate (ORR), Prostate-Specific Antigen (PSA) Response Rate, Radiographic Progression-Free Survival (rPFS), Time to Response (TTR)

Body systems

Oncology