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Study details
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LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis

Eli Lilly and Company
NCT IDNCT07186101ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

252

Study length

about 3.4 years

Ages

18–80

Locations

41 sites in AZ, CA, CO +16

About this study

Researchers are testing whether LY4268989, given with mirikizumab, is more effective than mirikizumab alone for adults with moderately to severely active ulcerative colitis. The trial will last about 118 weeks and involve approximately 252 participants.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take LY4268989
  • 2.Take LY4268989 Placebo
  • 3.Take Mirikizumab
PhasePhase 2
DrugMirikizumab

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low7%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

mirikizumab

Body systems

Gastroenterology