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Study details
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Effect of 2-HOBA in Persistent Immune Activation in Long COVID POTS

Vanderbilt University Medical Center
NCT IDNCT07189936ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

50

Study length

about 3.5 years

Ages

18+

Locations

1 site in TN

About this study

This trial is testing whether a treatment called 2-HOBA can help with immune markers and orthostatic tachycardia in people with Long COVID and POTS. The trial compares 2-HOBA to a placebo (an inactive substance) over 28 days.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take To Measure levels of circulating monocyte/ T cell doublets at Baseline
  • 2.Take To measure levels of circulating monocyte/ T cell doublets after 28 days of 2 HOBA treatment
  • 3.Take To measure levels of circulating monocyte/ T cell doublets after 28 days of Placebo treatment
  • +3 more
PhasePhase 2

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low15%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Body systems

Infectious