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Study details
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Transcutaneous Auricular Vagus Nerve Stimulation for Insomnia in Survivors of Childhood Acute Lymphoblastic Leukemia

St. Jude Children's Research Hospital
NCT IDNCT07191119ClinicalTrials.gov data as of Apr 2026
Target enrollment

40

Study length

about 3.9 years

Ages

20–50

Locations

1 site in TN

About this study

Researchers are testing whether transcutaneous auricular vagus nerve stimulation (tVNS) can help with insomnia in adults who have survived childhood acute lymphoblastic leukemia (ALL). Participants will use a device on their ear to stimulate the vagus nerve, either actively or as a sham. The trial will measure how well people stick to using the device and see if it improves sleep quality, reduces stress, and helps with thinking skills.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Participate in Neurocognitive and mental health outcomes
  • 2.Participate in Sleep Quality
  • 3.Use Soterix tVNS device
  • +1 more
Primary goalMean Change in Heart Rate Variability (ms)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low8%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Mean Change in Heart Rate Variability (ms)

Body systems

Oncology