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Study details
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Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants

AstraZeneca
NCT IDNCT07201558ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

48

Study length

about 2.6 years

Ages

18–65

Locations

3 sites in AL, CA, TX

About this study

Researchers are testing the safety and tolerability of surovatamig in adults with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE). The trial will also look at how the medication affects the body's processes after it is given as a subcutaneous injection.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Receive Surovatamig
PhasePhase 1
Primary goalSafety evaluation of surovatamig: Number of participants with treatment-emergent adverse events (TEAEs), serious adverse events (SAEs), adverse events of special interest (AESIs)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low15%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Safety evaluation of surovatamig: Number of participants with treatment-emergent adverse events (TEAEs), serious adverse events (SAEs), adverse events of special interest (AESIs), Safety of surovatamig: Incidence of AEs/SAEs leading to discontinuation of surovatamig, Tolerability of surovatamig: Incidence of treatment-related clinical laboratory abnormalities, Tolerability of surovatamig: Incidence of treatment-related vital signs abnormalities, Tolerability of surovatamig: Number of participants with abnormal ECG

Secondary: Serum Pharmacokinetics (PK) parameters of surovatamig - AUC0-last, Serum Pharmacokinetics (PK) parameters of surovatamig - AUCinf, Serum Pharmacokinetics (PK) parameters of surovatamig - AUCtau, Serum Pharmacokinetics (PK) parameters of surovatamig - Cmax

Body systems

Immune