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Study details
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Paracervical Injection and Opioid Use After Vaginal Hysterectomy for Prolapse

University of North Carolina, Chapel Hill
NCT IDNCT07213635ClinicalTrials.gov data as of Apr 2026
Phase

Phase 4

Target enrollment

56

Study length

about 1.2 years

Ages

18+

Sex

Female only

Locations

1 site in NC

About this study

This trial is testing if a numbing medicine injected around the cervix during vaginal hysterectomy with prolapse repair helps reduce opioid use after surgery. Researchers will compare people who receive this injection to those who get a saltwater placebo, looking at their pain medication needs and scores over several days following the procedure.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Bupivacaine-epinephrine
  • 2.Take Normal saline
PhasePhase 4
DrugBupivacaine-epinephrine
Routeinjection

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low10%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

vasopressor (Adrenergic agonist; stimulates heart and narrows blood vessels)

Drug routes

injection (Injection)

Endpoints

Secondary: Adverse events, Pain score

Body systems

Psychiatry / Mental Health