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Study details
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Orexin Receptor Antagonism for Alcohol Use Disorder

Ohio State University
NCT IDNCT07214207ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

250

Study length

about 4.8 years

Ages

18–65

Locations

1 site in OH

About this study

Researchers are testing if suvorexant, a drug that blocks orexin receptors, can help people with alcohol use disorder. The trial will compare suvorexant to a placebo (a fake pill) over 8 weeks to see if suvorexant reduces alcohol cravings and stress-related drinking.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Placebo
  • 2.Take Suvorexant 10 mg
PhasePhase 2
DrugSuvorexant 10 mg
Routeoral

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low13%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

suvorexant

Drug routes

oral (Oral Tablet)

Body systems

Psychiatry / Mental Health