Study details
Enrolling now
Oral Methadone in Cardiac Surgery
Mayo Clinic
NCT IDNCT07221617ClinicalTrials.gov data as of Apr 2026
Phase
Phase 4
Target enrollment
100
Study length
about 8 months
Ages
18+
Locations
1 site in MN
About this study
Researchers are testing whether oral methadone before surgery helps with post-operative pain compared to intravenous methadone. The trial will last 242 days and involve approximately 100 adults undergoing elective cardiac surgery.
Based on ClinicalTrials.gov records.
What participants do
- 1.Take Methadone, intravenously
- 2.Take Methadone, oral
PhasePhase 4
DrugMethadone, oral
Participation effort
Estimated from trial records. Details can vary by site.
Time + visits
Low10%
Logistics
Moderate50%
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
Drug classes
methadone (Long-acting opioid; prevents withdrawal and reduces craving)
Drug routes
oral
Endpoints
Secondary: Amount of opioid medication required throughout hospitalization, Pain scores after extubation
Body systems
Cardiology / Heart