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Study details
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A Study of Baricitinib for Delaying Type 1 Diabetes

Eli Lilly and Company
NCT IDNCT07222137ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

150

Study length

about 5.5 years

Ages

1–35

Locations

7 sites in FL, IA, KY +2

About this study

Researchers are testing if baricitinib can delay the onset of type 1 diabetes in people at high risk. The trial will last up to five years and involve approximately 150 participants.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Baricitinib
  • 2.Take Placebo
PhasePhase 3
DrugBaricitinib
Routeoral

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low8%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

baricitinib

Drug routes

oral (Oral Tablet)

Endpoints

Secondary: Change from Baseline in AUC Ratio (AUC C-peptide/AUC Glucose × 1000), Change from Baseline in Body Mass Index (BMI) Percentile, Change from Baseline in Glucose AUC, Change from Baseline in Glucose-Stimulated C-peptide Area Under the Curve (AUC), Change from Baseline in Height, Change from Baseline in Matsuda Index, Change from Baseline in Short Form 36 Version 2 Health Survey, Acute (SF-36v2), PK: Area Under the Concentration Versus Time Curve (AUC) of Baricitinib

Body systems

Endocrinology