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Study details
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A Study to Investigate Efficacy and Safety With SAR445399 in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Sanofi
NCT IDNCT07225569ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

144

Study length

about 1.9 years

Ages

18+

Locations

9 sites in AZ, CA, FL +2

About this study

This trial is testing a treatment called SAR445399 for hidradenitis suppurativa. This is a Phase 2 trial, meaning it's evaluating different doses of the drug to see if it works and is safe in adults with moderate to severe hidradenitis suppurativa.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Placebo
  • 2.Take SAR445399
PhasePhase 2

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low7%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Secondary: Absolute change from baseline to Week 16 in International Hidradenitis Suppurativa Severity Score System (IHS4), Absolute change from baseline to Week 16 in draining tunnel count, Absolute change from baseline to Week 16 in the Dermatology Life Quality Index (DLQI) score, Absolute change from baseline to Week 16 in the total Hidradenitis Suppurativa Quality of Life (HiSQoL) score, Change from baseline to Week 16 in Weekly average HS-SAQ score items, Change from baseline to Week 16 in the Hidradenitis Suppurativa Impact Assessment Questionnaire (HS-IAQ) score, Improvement in Peak Pruritus Numerical Rating Scale (PP-NRS) at Week 16, Number of participants with Treatment Emergent Adverse Events (TEAEs) Adverse Events of Special Interest (AESIs), and Serious Adverse Events (SAEs) including administration site reactions