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Study details
Enrolling now

Ultrasonic Neuromodulation of Cingulate Cortex for Fibromyalgia

SPIRE Therapeutics Inc.
NCT IDNCT07226648ClinicalTrials.gov data as of Apr 2026
Target enrollment

180

Study length

about 1.1 years

Ages

22+

Locations

4 sites in MN, NY, UT +1

About this study

This trial is testing a new noninvasive brain stimulation intervention called focused ultrasound to see if it can reduce pain in people with fibromyalgia. Participants will receive four treatments over one month and complete surveys at different points during the 16-week trial.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Use Focused Ultrasound
Primary goalNumerical Rating Scale - 11 (NRS-11) pain score

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low11%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Numerical Rating Scale - 11 (NRS-11) pain score

Secondary: Numerical Rating Scale - 11 (NRS-11) pain score, Numerical Rating Scale - 11 (NRS-11) pain score response rate, Patient Global Impression of Improvement (PGI-I), Patient Health Questionnaire-9 (PHQ-9), Patient-Reported Outcomes Measurement Information System (PROMIS-29) - Pain Interference Subscale

Body systems

Musculoskeletal