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Study details
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A 16-Week Study to Learn About Ritlecitinib for Hidradenitis Suppurativa

Pfizer
NCT IDNCT07228390ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

240

Study length

about 1.4 years

Ages

18–75

Locations

4 sites in CA, IN, MI +1

About this study

This trial is testing a treatment called Ritlecitinib in adults with hidradenitis suppurativa (HS), a condition causing painful red skin lumps. Participants will be randomly assigned to receive either Ritlecitinib or a placebo pill, taking it daily at home for about 24 weeks. It involves regular clinic visits and symptom tracking via an eDiary.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Placebo
  • 2.Take Ritlecitinib
PhasePhase 2
DrugRitlecitinib
Routeoral

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low5%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

ritlecitinib

Drug routes

oral (Oral Capsule)

Endpoints

Secondary: Absolute score and CFB in Hidradenitis Suppurativa Quality of Life (HiSQOL), CFB in Hidradenitis Suppurativa Symptom Daily Diary (HSSDD), CFB in skin pain NRS, at worst and on average, respectively, Incidence of treatment emergent adverse events (TEAE), adverse events (AE) and serious adverse events (SAE) leading to discontinuation, Percent CFB in skin pain NRS, at worst and on average, respectively, in participants with baseline skin pain NRS ≥3, Percent change from Baseline(CFB) in total AN count, Skin pain NRS30 (numeric rating scale) response, at worst and on average, respectively among participants with baseline skin pain NRS ≥3, Skin pain NRS50 response, at worst and on average, respectively among participants with baseline skin pain NRS ≥3.