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Study details
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A 2-part Phase 1b Clinical Trial to Evaluate CRB-913 in People with Obesity

Corbus Pharmaceuticals Inc.
NCT IDNCT07310901ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

252

Study length

about 8 months

Ages

18–75

Locations

15 sites in AL, AZ, CA +7

About this study

This trial is testing the safety of a new drug called CRB-913. It has two parts: Part 1 measures how the drug affects people's bodies, and Part 2 compares CRB-913 to a placebo (inactive pill) over 12 weeks to see if it helps with weight loss and blood levels of the drug.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take CRB-913
  • 2.Take Placebo
PhasePhase 1
Primary goalPart 1: To evaluate the PK of a single dose of CRB-913 - Cmax

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low14%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Part 1: To evaluate the PK of a single dose of CRB-913 - Cmax, Part 1: To evaluate the PK of a single dose of CRB-913 - T1/2, Part 1: To evaluate the PK of a single dose of CRB-913 - Tmax, Part 2: To evaluate the safety of CRB-913 - TEAE

Secondary: Part 1: To evaluate the safety of a single dose of CRB-913 - TEAE, Part 2: To evaluate the PK of CRB-913 - Cmax, Part 2: To evaluate the PK of CRB-913 - Tmax