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Study details
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A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)

Merck Sharp & Dohme LLC
NCT IDNCT07318558ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Ages

18+

Sex

Female only

Locations

1 site in FL

About this study

This Phase 3 study is testing Bevacizumab in people with neoplasms. The primary outcome being measured is Progression-Free Survival (PFS).

Based on ClinicalTrials.gov records.

PhasePhase 3
DrugBevacizumab
Routeinfusion
Primary goalProgression-Free Survival (PFS)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low9%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

bevacizumab

Drug routes

infusion

Endpoints

Primary: Progression-Free Survival (PFS)

Secondary: Change From Baseline in Abdominal/Gastrointestinal (GI) Symptoms Combined Score Using the EORTC QLQ-Ovarian Cancer Module 28 (OV28), Change From Baseline in Global Health Status/Quality of Life (GHS/QoL) Combined Score (Items 29 and 30) Using the European Organisation for Research and Treatment of Cancer QoL Questionnaire-Core 30 (EORTC QLQ-C30), Change From Baseline in Physical Functioning Combined Score (Items 1 to 5) Using EORTC QLQ-C30, Change From Baseline in Role Functioning Combined Score (Items 6 and 7) Using EORTC QLQ-C30, Number of Participants Who Discontinue Study Treatment Due to an AE, Number of Participants Who Experience an Adverse Event (AE), Overall Survival (OS), Progression-Free Survival 2 (PFS2)

Body systems

Oncology