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Study details
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A Study of Pasritamig (JNJ-78278343) in Combination With JNJ-86974680 for Treatment of Prostate Cancer

Janssen Research & Development, LLC
NCT IDNCT07319871ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

40

Study length

about 1.1 years

Ages

18+

Locations

3 sites in FL, NY, OH

About this study

This trial is testing a treatment combination of JNJ-86974680 and Pasritamig to see if it's safe and effective for people with advanced prostate cancer. The goal is to find the best dose of this combination that can be used in future studies.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take JNJ-86974680
  • 2.Take Pasritamig
PhasePhase 1
Primary goalNumber of Participants With Adverse Events (AEs) by Severity

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low8%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Number of Participants With Adverse Events (AEs) by Severity, Part 1: Number of Participants With Dose-Limiting Toxicity (DLT)

Secondary: Duration of Response (DOR), Objective Response Rate (ORR), Prostate-Specific Antigen (PSA) Response Rate, Radiographic Progression-Free Survival (rPFS), Time to Response (TTR)

Body systems

Oncology