Efficacy and Safety of Eloralintide in People With Osteoarthritis Knee Pain and Obesity or Overweight
Phase 3
900
about 2.3 years
18+
34 sites in AL, AZ, CA +12
About this study
This trial is testing a treatment called Eloralintide to see if it helps people with osteoarthritis knee pain who are also overweight or obese. The trial will last about 75 weeks, including screening.
Based on ClinicalTrials.gov records.
What participants do
- 1.Take Eloralintide
- 2.Take Placebo
Participation effort
Estimated from trial records. Details can vary by site.
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
Primary: Change from Baseline in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain Subscale Score, Percent Change from Baseline in Body Weight
Secondary: Achievement of Improved Categorical Shift in Patient Global Impression of Severity (PGIS) - Target Knee Pain, Change from Baseline WOMAC Pain Subscale Score, Change from Baseline in Average Pain Intensity Numeric Rating Scale (API-NRS) Score, Change from Baseline in Body Mass Index (BMI), Change from Baseline in Distance Walked During the 6-Minute Walk Test, Change from Baseline in Health Status EQ-5D-5L Health State Utility, Change from Baseline in SF-36v2 Acute Form Domain Scores With Exception of the Physical Functioning Domain Score, Change from Baseline in Short Form-36 (SF-36 v2) Acute Form Physical Functioning Domain Score
Endocrinology, Musculoskeletal