Study details
Enrolling now
Carbon Dioxide Administration and Brain Waste Clearance
Andrew Mayer
NCT IDNCT07357090ClinicalTrials.gov data as of Apr 2026
Target enrollment
200
Study length
about 6.1 years
Ages
18–82
Locations
1 site in NM
About this study
This trial is testing whether different levels of carbon dioxide can safely increase the movement of proteins from the brain into the blood, which could help clear waste products. The study will involve adults with or without a history of traumatic brain injury receiving varying doses of CO2 over several months.
Based on ClinicalTrials.gov records.
What participants do
- 1.Hypercapnia task performed during fMRI
Primary goalProtein Efflux (Surrogate Measure of Brain Waste Clearance)
Participation effort
Estimated from trial records. Details can vary by site.
Time + visits
Low9%
Logistics
Moderate50%
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
Endpoints
Primary: Protein Efflux (Surrogate Measure of Brain Waste Clearance)