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Study details
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A Clinical Study of MK-4082 in Healthy Overweight Participants (MK-4082-002)

Merck Sharp & Dohme LLC
NCT IDNCT07388667ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Ages

18–60

Locations

5 sites in CA, FL, MO +1

About this study

This Phase 1 study is focused on people with healthy volunteers. The primary outcome being measured is Number of Participants Who Discontinue Study Treatment Due to an AE.

Based on ClinicalTrials.gov records.

PhasePhase 1
Primary goalNumber of Participants Who Discontinue Study Treatment Due to an AE

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low6%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Number of Participants Who Discontinue Study Treatment Due to an AE, Number of Participants Who Experience an Adverse Event (AE)

Secondary: Apparent Clearance (CL/F) of MK-4082, Apparent Terminal Half-life (t1/2) of MK-4082, Change from Baseline in Body Mass Index (BMI), Change from Baseline in Body Weight, Maximum Plasma Concentration (Cmax) of MK-4082, Time to Maximum Plasma Concentration (Tmax) of MK-4082