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Study details
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Treatment of Participants With Primary or Secondary Progressive Multiple Sclerosis

Tr1X, Inc.
NCT IDNCT07477639ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1/2

Ages

18–65

Locations

2 sites in KS, MO

About this study

This Phase 1/Phase 2 study is testing Bendamustine in people with multiple sclerosis. The primary outcome being measured is To assess the safety and tolerability of TRX319 infusion in subjects with Primary Progressive or Secondary Progressive Multiple Sclerosis.

Based on ClinicalTrials.gov records.

PhasePhase 1/Phase 2
DrugBendamustine
Primary goalTo assess the safety and tolerability of TRX319 infusion in subjects with Primary Progressive or Secondary Progressive Multiple Sclerosis

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low13%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

bendamustine

Endpoints

Primary: To assess the safety and tolerability of TRX319 infusion in subjects with Primary Progressive or Secondary Progressive Multiple Sclerosis.

Secondary: To evaluate disease response, as measured by the Neurostatus Expanded Disability Status Scale (EDSS), To evaluate the effects of TRX319 on disease progression/reactivation by gadolinium-enhancing MRI

Body systems

Neurology